{"id":20852,"date":"2024-06-25T11:34:02","date_gmt":"2024-06-25T09:34:02","guid":{"rendered":"https:\/\/ela-international.preprod.melisagency.fr\/?post_type=news_research&#038;p=20852"},"modified":"2024-07-11T17:26:10","modified_gmt":"2024-07-11T15:26:10","slug":"selective-galactosylceramidase-ablation-to-study-the-pathogenesis-of-krabbe-leukodystrophy","status":"publish","type":"news_research","link":"https:\/\/elainternational.eu\/en\/actualites_recherche\/selective-galactosylceramidase-ablation-to-study-the-pathogenesis-of-krabbe-leukodystrophy\/","title":{"rendered":"Selective galactosylceramidase ablation to study the pathogenesis of Krabbe leukodystrophy"},"content":{"rendered":"\n\n<section class=\"contenus-titre-texte\">\n    <div class=\"contenus-titre-texte-container container-content\">\n        <div class=\"contenus-titre-texte-header mobile-flex-display\">\n                        <h3><strong>Selective galactosylceramidase ablation to study the pathogenesis of Krabbe leukodystrophy<\/strong><\/h3>\n                                <\/div>\n            <\/div>\n<\/section>\n\n\n<section class=\"infos-ribbon\">\n    <div class=\"infos-ribbon-container container-content mobile-flex-display\">\n        <p><em>Laurence Wrabetz &#8211; SUNY Buffalo\/ Hunter James Kelly Research Institute, Buffalo, USA &#8211; ELA2018-023I4<\/em><\/p>\n            <\/div>\n<\/section>\n\n\n\n\n\n<section class=\"contenus-titre-texte\">\n    <div class=\"contenus-titre-texte-container container-content\">\n        <div class=\"contenus-titre-texte-header mobile-flex-display\">\n                        <h5><strong>Description of the project<\/strong><\/h5>\n                                <\/div>\n                    <div class=\"contenu-texte\">\n                <p>Krabbe leukodystrophy (KD) is a progressive and fatal neurologic lysosomal storage disorder that usually affects infants and causes death before two to three years of age. Hematopoietic Stem Cell Therapy extends the long-term survival with improved quality of life for KD patients, but it is not a cure. Using our newly developed KD animal model, we will identify which brain cell(s) needs to be efficiently cured with therapy.<\/p>\n<p style=\"font-weight: 400;\">Project financed by ELA up to:\u00a0 71 082 \u20ac<\/p>\n            <\/div>\n            <\/div>\n<\/section>","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":0,"parent":0,"template":"","news_research_categories":[127],"news_research_tags":[129,114],"class_list":["post-20852","news_research","type-news_research","status-publish","hentry","news_research_categories-project","news_research_tags-krabbe-disease","news_research_tags-leukodystrophy"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Selective galactosylceramidase ablation to study the pathogenesis of Krabbe leukodystrophy - ELA International<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/elainternational.eu\/en\/actualites_recherche\/selective-galactosylceramidase-ablation-to-study-the-pathogenesis-of-krabbe-leukodystrophy\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Selective galactosylceramidase ablation to study the pathogenesis of Krabbe leukodystrophy - 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